Nutramedix, BURBUR-PINELLA Detox/Brain -Nerve Cleanse

CANCER

Kadan, S., Rayan, M., & Rayan, A. (2013). Anticancer activity of anise (Pimpinella anisum L.) seed extract. The Open Nutraceuticals Journal, 6(1). Full Article

ANTIBACTERIAL

Al-Bayati, F. A. (2008). Synergistic antibacterial activity between Thymus vulgaris and Pimpinella anisum essential oils and methanol extracts. Journal of Ethnopharmacology, 116(3), 403-406. Full Article

Bussmann, R. W., Sharon, D., Perez, F., Díaz, D., Ford, T., Rasheed, T., & Silva, R. (2008). Antibacterial activity of Northern-Peruvian Medicinal Plants-a low-cost laboratory approach to assess biological activity. Arnaldoa, 15(1), 127-148. Full Article

Akhtar, A., Deshmukh, A. A., Bhonsle, A. V., Kshirsagar, P. M., & Kolekar, M. A. (2008). In vitro antibacterial activity of Pimpinella anisum fruit extracts against some pathogenic bacteria. Veterinary World, 1(9), 272-274. Full Article

ANTIOXIDANT

Lock, O., Castillo, P., Doroteo, V., & Rojas, R. (2005). Antioxidant activity in vitro of selected Peruvian medicinal plants. Acta Horticulturae, 675, 103-106. Full Article

 Gülçın, İ., Oktay, M., Kıreçcı, E., & Küfrevıoǧlu, Ö. İ. (2003). Screening of antioxidant and antimicrobial activities of anise (Pimpinella anisum L.) seed extracts. Food Chemistry, 83(3), 371-382. Full Article

ANTICONVULSANT

Karimzadeh, F., Hosseini, M., Mangeng, D., Alavi, H., Hassanzadeh, G. R., Bayat, M., ... & Gorji, A. (2012). Anticonvulsant and neuroprotective effects of Pimpinella anisum in rat brain. BMC Complementary and Alternative Medicine, 12(1), 76. Full Article

Pourgholami, M. H., Majzoob, S., Javadi, M., Kamalinejad, M., Fanaee, G. H. R., & Sayyah, M. (1999). The fruit essential oil of Pimpinella anisum exerts anticonvulsant effects in mice. Journal of Ethnopharmacology, 66(2), 211-215. Full Article

ANTIFUNGAL

Yazdani, D., Rezazadeh, S. H., Amin, G. H., Abidin, Z., Shahnazi, S., & Jamalifar, H. (2009). Antifungal activity of dried extracts of anise (Pimpinella anisum L.) and star anise (Illicium verum Hook. f.) against dermatophyte and saprophyte fungi. Journal of Medicinal Plants, 1(29), 24-29. Full Article

Kosalec, I., Pepeljnjak, S., & Kuštrak, D. (2005). Antifungal activity of fluid extract and essential oil from anise fruits (Pimpinella anisum L., Apiaceae).Acta Pharmaceutica, 55(4), 377-385. Full Article

Shukla, H. S., & Tripathi, S. G. (1987). Antifungal substance in the essential oil of anise (Pimpinella anisum L.). Agricultural and Biological Chemistry, 51(7), 1991-1993. Full Article

ANTIMICROBIAL

Gende, L. B., Maggi, M. D., Fritz, R., Eguaras, M. J., Bailac, P. N., & Ponzi, M. I. (2009). Antimicrobial activity of Pimpinella anisum and Foeniculum vulgare essential oils against Paenibacillus larvae.Journal of Essential Oil Research, 21(1), 91-93. Full Article

Rojas, R., Bustamante, B., Bauer, J., Fernández, I., Albán, J., & Lock, O. (2003). Antimicrobial activity of selected Peruvian medicinal plants. Journal of Ethnopharmacology, 88(2-3), 199-204. Full Article

ANTIVIRAL

Lee, J. B., Yamagishi, C., Hayashi, K., & Hayashi, T. (2011). Antiviral and immunostimulating effects of lignin-carbohydrate-protein complexes from Pimpinella anisum. Bioscience, Biotechnology, and Biochemistry, 75(3), 459-465. Full Article

Shukla, H. S., Dubey, P., & Chaturvedi, R. V. (1989). Antiviral properties of essential oils of Foeniculum vulgare and Pimpinella anisum L. Agronomie, 9(3), 277-279. Full Article

RELAXANT

Tirapelli, C. R., de Andrade, C. R., Cassano, A. O., De Souza, F. A., Ambrosio, S. R., da Costa, F. B., & de Oliveira, A. M. (2007). Antispasmodic and relaxant effects of the hidroalcoholic extract of Pimpinella anisum (Apiaceae) on rat anococcygeus smooth muscle. Journal of Ethnopharmacology, 110(1), 23-29. Full Article

Boskabady, M. H., & Ramazani-Assari, M. (2001). Relaxant effect of Pimpinella anisum on isolated guinea pig tracheal chains and its possible mechanism (s). Journal of Ethnopharmacology, 74(1), 83-88. Full Article

VARIOUS PROPERTIES

Shojaii, A., & Abdollahi Fard, M. (2012). Review of pharmacological properties and chemical constituents of Pimpinella anisum. ISRN Pharmaceutics, 2012. Full Article

Cowden Support Program for Lyme: Observational Study – Dublin, Ireland – June, 2012 Armin Schwarzbach, MD PhD Full Video

"I was diagnosed with Lyme Disease and began taking the Cowden Support Program.  As I detoxed, my body went into a Herxheimer reaction and it completely subsided when I began taking Burbur-Pinella!"  -A.E.

“This is very powerful and helpful for lyme disease herxheimers and brain thickness and tingling and numbness. I take 8 drops per 8 oz water, as much as i need. I'm so glad I found this.” –M.Y

“This product was recommended by my Integrated Medicine doctor and is definitely helping to calm my nerves and nervous ticks that have come with Lyme and co-infections. It seems to help my overall mood also. I'm very thankful for this product!” –R.F

"Six years ago, I kept having back pain; was diagnosed with beginning stages of kidney failure.  My naturopath put me on Burbur-Pinella a few months ago and the pain and all effects of kidney failure are gone.  Burbur-Pinella is a miraculous product."  -N.A.

"A friend recommended that I try Burbur Pinella since bronchitis had gotten a hold of me BIG TIME.  It eliminated my cough TOTALLY!!!"  -R.E.

General Detox Aid: Take 20 drops in 4 oz. of water 1-2 times daily.

Mild Toxicity, Brain Fog: Take 10 drops 3-4 times daily.

May be taken several times per day as needed.

Moderate to Severe Toxicity and Herxheimer Reaction (healing crisis): Take 20 drops every 15 minutes in 2 oz. of water until symptoms are resolved.

Can also put 4 droppers full (approximately 120 drops) in at least 16 oz. of water and sip over a 2-hour period, repeating until symptoms are resolved.

An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Burbur did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article